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Blood sugar levels gradually returned to normal over several days, and no patient in the study reported blood sugar control problems lasting longer than 5 days, buying steroids from dark webstores or getting insulin from a black market source. In a study published in Science Translational Medicine, the team of researchers showed that this approach could improve patients' clinical outcomes. "By targeting glycolysis more directly, the ketogenic diet may also be helpful for people who have type 2 diabetes or hypoglycemia, which might have other detrimental effects on blood sugar control," said lead study author Michael D. Stokes, MD, PhD, an assistant professor of medicine in the Division of Diabetes at the Icahn School of Medicine at Mount Sinai. The ketogenic diet is an extreme diet that reduces consumption of carbohydrates, especially simple sugars, and increases animal-based protein, which leads one to think that it would cause blood sugar to skyrocket. However, an increase in protein has been found to be beneficial in reducing the risks of type 2 diabetes. In the study, researchers looked at the ketogenic diet in four diabetic patients who were overweight, had hyperglycemia and a poor control of the blood glucose. The patients consumed a low-carbohydrate diet and low-sugar beverages until their blood glucose levels were below 80 mg/dl. Each patient began the ketogenic diet with 1,200 grams of fat and calories with about 20 percent of that coming from carbohydrates. Over the course of the diet, which lasted for 16 weeks, levels of blood glucose fell significantly, and then stabilized and started recovering to normal levels. After adjusting for baseline levels of blood glucose, which the researchers didn't know about, participants' blood sugar levels remained below 130 mg/dl for the entire study. A few of the patients complained of low levels of appetite, fatigue or other symptoms of type 2 diabetes. However, none of their blood sugar levels rose above 100 mg/dl for more than a week, and none showed serious complications after the diet ended. The patients also experienced improvements in insulin sensitivity and blood sugar control, compared to patients who ate other diets that increased carbohydrate consumption. In addition, the ketogenic diet was very beneficial in lowering levels of oxidative stress. "Ketogenic diets, particularly the low-carbohydrate, high-protein diet, are known to reduce the oxidation of fats and lipids and to promote the repair of the mitochondrial network," said Stokes. "Mitochondria are responsible for storing energy in the form of ATP. With this increased energy storage, we think less ATP is needed for energy generation in the Related Article: